The Appendix Cancer Connection
a 501(c) 3 non-profit corporation devoted to
providing education, support and hope to those diagnosed with Appendix Cancer
and Peritoneal Surface Malignancies


Main Page/Survivor Story
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About Appendix Cancer


Malignant Carcinoid
Mucinous Adenocarcinoma and Pseudomyxoma peritonei (PMP)
Adenocarcinoid (Goblet Cell Carcinoid)
Signet Ring Cell Carcinoma (Signet Ring Adenocarcinoma)


Physicians and Facilities Treating Appendix Cancer
Cytoreduction Surgery
Hyperthermic Intraperitoneal  Chemotherapy (HIPEC)
Complications of Cytoreduction Surgery and HIPEC
Systemic (IV) Chemotherapy for Appendiceal Cancer
After Treatment Follow-Up


Hair Loss and Chemotherapy
Colostomy Information
Herbal and Complimentary Care
Hospice Care


Peritoneal Surface Malignancy
Peritoneal Carcinomatosis
Staging of Peritoneal Cancer


Clinical Trials
General Practical Assistance (Travel, Insurance, Medical Bills) 


Right foot, Left Foot, Breathe.....





Malignant Carcinoid of the Appendix


  • Carcinoid tumors are the most common of all appendix tumors.  They are neuroendocrine tumors, meaning they are tumors that can create and release hormones into the bloodstream, although this usually only happens with metastatic disease (carcinoid tumors that have spread beyond the appendix to other areas of the body).  Carcinoids are small yellow tumors usually found in the part of the appendix farthest away from where the appendix attaches to the colon or near the tip of the appendix.  The tumors usually do not block the appendix and cause appendicitis.  They are most often found unexpectedly during other abdominal or pelvic surgeries, for example surgeries to remove the gall bladder, hysterectomy etc.   The tumors are small, slow growing and rarely metastasize (spread to other areas).  The term "malignant" is applied to carcinoids that have metastasized to other areas of the body.


  • Carcinoids usually cause no symptoms.  Symptoms of carcinoid syndrome may rarely occur with metastasis, especially metastasis to the liver.


  • Tumors less then 1 cm in diameter are treated with appendectomy (surgical removal of the appendix) only.  Appendectomy is usually considered 100% curative for these small tumors. Over 95% of carcinoid tumors of the appendix are less than 2 cm in size.  

  • Tumors 1.5-2 cm may be treated with appendectomy only or with right hemicolectomy (removal of up to half of the right side of the colon); there is disagreement in the medical community in regards to treatment in for carcinoids this size.    

  • Carcinoids greater than 2 cm are more likely to metastasize.  Surgical treatment for these larger carcinoids is appendectomy, right hemicolectomy (removal of up to half of the right side of the colon) and removal of local lymph nodes.  

  • When carcinoid tumors spread (metastasize), they most commonly spread to the liver or lymph nodes.  Chemotherapy is not very successful in this disease, with 30% limited response to chemotherapy reported.  These metastatic tumors may be removed  surgically.

Risk Factors: 

  • Appendiceal carcinoids are more common in women by a ratio of 2:1 or 3:1.  Average age 4th or 5th decade of life. No other known risk factor


  • Overall 5 year survival reported as high as 90% in some medical research

Related Links

Carcinoid Foundation

Caring for Carcinoid Foundation: About Carcinoid

National Cancer Institute: Gastrointestinal carcinoid tumor

American Cancer Society: Tumors of the Appendix

Gastrointestinal Carcinoid Tumors

Carcinoid Tumor of the Appendix: Treatment and Prognosis

This website is for informational and educational purposes only. Readers are encouraged to confirm the information contained herein with other sources. The information on this website is not complete and not intended to replace medical advice offered by physicians or health care providers.  Patients and consumers should review the information carefully with their professional health care provider.  

 Copyright 2005- 2010 C. Langlie-Lesnik  RN BSN  All rights Reserved

Last Updated   02/12/2010 12:49:52 PM